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Cat. No. | Product Name | Target | Signaling Pathways |
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TP1916L1 |
[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base) |
Bombesin Receptor | GPCR/G Protein |
[D-Phe12,Leu14]-Bombesin acetate 抑制铃蟾素刺激的分泌。 | |||
TP2239L |
[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate(108437-87-2 free base) |
Bombesin Receptor | GPCR/G Protein |
[D-Phe12]-Bombesin acetate 抑制铃蟾素刺激的分泌。 | |||
T75909 |
[Nphe1]Nociceptin(1-13)NH2 TFA
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[Nphe1]Nociceptin(1-13) NH2 TFA 是一种 Nociceptin/orphanin FQ (NC)内源性配体,是一种选择性和竞争性的 ociceptin receptor 拮抗剂,不具有激动剂活性。[Nphe1]nociceptin(1-13)NH2 选择性结合重组 nociceptin 受体(pKi=8.4),拮抗 nociceptin 对 CHO 细胞中 cAMP 积累的抑制作用(pA2=6.0)。[Nphe1]Nociceptin(1-13)NH2 有可能作为一种止痛试剂。 | |||
T76602 |
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
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(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 作为一种CRF拮抗剂,能有效阻断IL-1a诱发的黄体生成素 (LH) 抑制作用。 | |||
T76632 |
(Phe13,Tyr19)-MCH (human, mouse, rat)
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(Phe13,Tyr19)-MCH (human, mouse, rat) 作为一种高效的 SLC-1 与 S643b 受体配体,可充当这两种受体的激动剂。 | |||
TP1916 |
[D-Phe12,Leu14]-Bombesin
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Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo. | |||
TP1988 |
[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
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Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively) | |||
TP2239 |
[D-Phe12]-Bombesin
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Others | Others |
Bombesin receptor antagonist | |||
TP1987 |
[Nphe1]Nociceptin(1-13)NH2
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Selective and competitive nociceptin receptor antagonist, devoid of any agonist activity. Binds selectively to recombinant nociceptin receptors (pKi = 8.4), and competitively antagonizes the actions of nociceptin in vitro and in vivo. |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01114 |
NPC2 Protein, Human, Recombinant (His)
HE1,Niemann-Pick disease, type C2,EDDM... |
Human | HEK293 Cells |
NPC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is P61916-1. | |||
TMPY-04990 |
NPC2 Protein, Mouse, Recombinant (His)
2700012J19Rik,HE1,AA4080... |
Mouse | HEK293 Cells |
NPC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.9 kDa and the accession number is Q9Z0J0. | |||
TMPY-03658 |
ETHE1 Protein, Human, Recombinant (His)
YF13H12,HSCO,ethylmalonic encephalopathy <... |
Human | E. coli |
ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic en... |