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Cat. No.	Product Name	Target	Signaling Pathways
T78767	HDAC-IN-60	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC-IN-60 (化合物21a) 作为一种高效HDAC抑制剂，能增强细胞内ROS生成，导致DNA损伤，阻碍G2/M期细胞周期，且触发线粒体相关凋亡途径促进细胞死亡。
T60082	HDAC-IN-40	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HDAC-IN-40 是一种有效的基于烷氧基酰胺的 HDAC 抑制剂，对 HDAC2 和 HDAC6 的 Ki 分别为 60 nM 和 30 nM。HDAC-IN-40 具有抗肿瘤作用。
T6678	Splitomicin 1-Naphthalenepropanoic Acid,斯普利特麻一辛	Sirtuin; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Splitomicin (1-Naphthalenepropanoic Acid) 是 NAD(+) 依赖性组蛋白去乙酰化酶 Sir2p 的特异性抑制剂，可抑制酵母提取物中 HDAC，IC50为 60 μM。
T36629	Givinostat
	Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF3056. At 25, 50, and 100 nM, Givinostat reduced IL-1β secretion more than 70%. Givinostat (ITF-2357) suppresses the production of IL-6 in PBMCs stimulated with TLR agonists as well as the combination of IL-12 plus IL-18. IL-6 secretion decreases to 50% at 50 nM Givinostat, but at 1...