Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4174 |
Guajadial
|
Glucokinase | Metabolism |
Guajadial shows α-glucosidase inhibitory activities significantly and its activity was better than that of Acarbose.Guajadial may act as Selective Estrogen Receptors Modulators (SERMs), therefore holding significant potential for anticancer therapy, it ex | |||
TN5348 | Guajadial F | ||
Guajadial F acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. Guajadial F shows cytotoxicity against five human cancer cell lines. | |||
TN5347 |
Guajadial E
|
||
Guajadial E shows cytotoxicity against five human cancer cell lines. | |||
TN5349 | Guajadial D | ||
Guajadial D shows cytotoxicity against five human cancer cell lines. | |||
TN4172 |
Guajadial B
|
Topoisomerase | DNA Damage/DNA Repair |
Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM toward A549 cells. | |||
TN4173 |
Guajadial C
|
Topoisomerase | DNA Damage/DNA Repair |
Guajadial C acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. It shows cytotoxicity against five human cancer cell lines. | |||
TN3969 | Epiguajadial B | Others | Others |
Epiguajadial B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3969,CAS号为 1411629-26-9。 |