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Cat. No. Product Name Target Signaling Pathways
T5471 GUANABENZ

Adrenergic Receptor GPCR/G Protein; Neuroscience
GUANABENZ 是一种中枢 alpha-2 肾上腺素能激动剂。它的作用机制是作为肾上腺素能 α2-激动剂。
T21957 Guanabenz hydrochloride

NE56490

Adrenergic Receptor GPCR/G Protein; Neuroscience
Guanabenz hydrochloride (NE56490) 是一种具有降血压作用的口服活性 α2-肾上腺素受体激动剂。
T6522 Guanabenz Acetate

Wy8678 acetate,BR-750,4-咪唑乙酸盐酸盐,Wytensin

Adrenergic Receptor GPCR/G Protein; Neuroscience
Guanabenz Acetate (Wytensin) 是一种 α2 肾上腺素激动剂,可用于高血压的研究。
T60304 (E)-Guanabenz

(E)-Guanabenz ((E)-Wy-8678) 是一种具有口服活性的中枢α2-肾上腺素受体 (α2-adrenoceptor)激动剂。(E)-Guanabenz 具有抗高血压活性,通过刺激中枢 α2- 肾上腺素受体,并减少交感神经向外周的净流出而起作用。(E)-Guanabenz z 也直接结合并抑制 GADD34,具有神经保护活性。(E)-Guanabenz 可用于研究高血压和帕金森病。
T38146 Chloroguanabenz (acetate)

Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz . It inhibits prion formation in yeast and mammalian cell-based assays. Chloroguanabenz reduces the levels of both soluble and aggregated forms of the truncated Huntingtin derivative Htt48 in an HEK293T cellular model of Huntington's disease.
T9174 Icerguastat

Sephin 1,lcerguastat,IFB-088

Phosphatase Metabolism
Icerguastat (IFB-088) 是一种缺乏 α2-肾上腺素能活性的 Guanabenz 衍生物,是一种磷酸酶调节亚单位 PPP1R15A (R15A)的选择性抑制剂。它能够抑制 eIF2α 去磷酸化,从而延长保护反应。它具有抗朊病毒作用。
T38187 6-Aminophenanthridine

6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz . 6-Aminophenanthridine (300 μM) inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive w...

化合物

GUANABENZ
Cat.No: T5471
Synonym:
Target: Adrenergic Receptor
Guanabenz hydrochloride
Cat.No: T21957
Synonym: NE56490
Target: Adrenergic Receptor
Guanabenz Acetate
Cat.No: T6522
Synonym: Wy8678 acetate,BR-750,4-咪唑乙酸盐酸盐,Wytensin
Target: Adrenergic Receptor
(E)-Guanabenz
Cat.No: T60304
Synonym:
Target:
Chloroguanabenz (acetate)
Cat.No: T38146
Synonym:
Target:
Icerguastat
Cat.No: T9174
Synonym: Sephin 1,lcerguastat,IFB-088
Target: Phosphatase
6-Aminophenanthridine
Cat.No: T38187
Synonym:
Target:
TargetMol Loading
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