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Cat. No. Product Name Target Signaling Pathways
T11824LL Lanraplenib

GS-9876

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Lanraplenib (GS-9876) 是高效的、选择性的、口服具有活力的 SYK 抑制剂 (IC50=9.5 nM) ,能够用于炎症性疾病的研究。它通过糖蛋白 VI (GPVI) 受体抑制血小板中的 SYK 活性,而不会延长猴子或人类的出血时间 (BT)。
T11824L Lanraplenib monosuccinate

GS-9876 monosuccinate

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.
T11824 Lanraplenib succinate

GS-9876 succinate

Syk Angiogenesis; Tyrosine Kinase/Adaptors
Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.

化合物

Lanraplenib
Cat.No: T11824LL
Synonym: GS-9876
Target: Syk
Lanraplenib monosuccinate
Cat.No: T11824L
Synonym: GS-9876 monosuccinate
Target: Syk
Lanraplenib succinate
Cat.No: T11824
Synonym: GS-9876 succinate
Target: Syk
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