Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15207 |
Eleclazine hydrochloride
GS 6615 hydrochloride |
Sodium Channel | Membrane transporter/Ion channel |
Eleclazine hydrochloride (GS 6615 hydrochloride) 是新型 Na+电流抑制剂,IC50是0.7 uM。 | |||
T70637 |
FRAN-12
|
||
FRAN-12 is a histamine and 5-hydroxytryptamine antagonist with pressor properties. | |||
T71945 |
Eleclazine free base
|
||
Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart’s electrical cycle) in patients with long QT-3 (LQT3) syndrome. LQT3 is a genetic disorder that prolongs the heart’s QTc interval and can cause life-threatening cardiac arrhyth... |