Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4312 |
GPR120 Agonist 2
GPR120 receptor agonist |
GPR | Endocrinology/Hormones; GPCR/G Protein |
GPR120 Agonist 2 是一种选择性 GPR120激动剂。 | |||
T15413 |
GPR120 Agonist 3
GPR120-IN-1 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
GPR120 Agonist 3 (GPR120-IN-1) 是一种有效的、选择性的 Gpr120激动剂,logEC50为 −7.62。 | |||
T22967 |
MEDICA16
MEDICA 16 |
GPR; Others; ATP Citrate Lyase | Endocrinology/Hormones; GPCR/G Protein; Metabolism; Others |
MEDICA16 是 GPR40 的特异性激动剂以及 GPR120 的部分激动剂。 MEDICA16 是一种 ATP-柠檬酸裂解酶抑制剂,可显着降低腓肠肌中的细胞内 TG 含量,同时增加胰岛素敏感性。 | |||
T34968 |
TUG-905
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TUG-905 is an agonist for free fatty acid receptor 4 (FFA4/GPR120), and TUG-905 has the potential to treat agitation. | |||
T36634 |
ZQ 16
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Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro. Liu et al (2016) Design and synthesis of 2-alkylpyrimidine-4,6-diol and 6-alkylpyridine-2,4-diol as potent GPR84 agonists. ACS Med.Chem.Lett. 7 579 PMID:27326330 |Zhang et al (2016) Discovery and characte... |