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Search Results for " gpc3 "

1

抑制剂 & 化合物

1

天然产物

16

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T75134	MC-GGFG-AM-(10Me-11F-Camptothecin)
	MC-GGFG-AM-(10Me-11F-Camptothecin) 是ZW251合成的Linker-Payload偶联物。ZW251是靶向人GPC3的抗体-活性分子偶联物(ADC)，包括人源化IgG1抗体、喜树碱(camptothecin)类的扑异构酶1抑制剂ZD06519及连接子（马来酰亚胺锚定和甘酰甘酰苯丙酰甘氨酸(GGFG)-氨基甲基(AM)可切割连接体）。该药物对人和食蟹猴GPC3具高亲和力，在表达GPC3的HCC细胞系中快速内化并可对GPC3阴性癌细胞进行旁观者介导杀伤。

化合物

MC-GGFG-AM-(10Me-11F-Camptothecin)

Cat.No: T75134

Cat. No.	Product Name	Target	Signaling Pathways
T3932	Viscidulin I	Others	Others
	Viscidulin I 存在于黄芩中，是一种天然产物。

天然产物

Cat.No: T3932

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00337	GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated GPC3,GTR2-2,MXR7,Intestinal protein OCI-5,...	Human	HEK293 Cells
	GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-180 and 36-44 KDa and the accession number is P51654.
TMPJ-01423	GPC3 Protein, Rhesus macaque, Recombinant (His) OCI5,GPC3,Glypican-3,MXR7,Intesti...	Rhesus	HEK293 Cells
	GPC3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38 and 65-120 KDa and the accession number is XP_005594665.1.
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His) SGBS1,DGSX,SGBS,MXR7,OCI-5,Glypican 3,SGB,SDYS,GTR2...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62 kDa and the accession number is P51654-1.
TMPY-00502	Glypican 3/GPC3 Protein, Mouse, Recombinant (His) OCI-5,glypican 3	Mouse	Baculovirus Insect Cells
	Glypican 3/GPC3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 62 kDa and the accession number is Q3TWB2.
TMPK-00336	GPC3 Protein-VLP, Human, Recombinant Glypican 3,SGB,SGBS1SDYS,DGSX,OCI-5,OCI5,GTR2-2,	Human	E. coli
	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. GPC3 Protein-VLP, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 kDa and the accession ...
TMPK-00337	GPC3 Protein-VLP, Human, Recombinant (aa 438-554) OCI-5,SDYS,SGB,OCI5,MXR7,GTR2-2,GPC3,Glypi...	Human	HEK293 Cells
	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. GPC3 Protein-VLP, Human, Recombinant (aa 438-554) is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and th...
TMPH-03307	Glypican 3/GPC3 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Glypican 3/GPC3 Protein, Rat, Recombinant (His) is expressed in Yeast.
TMPY-06751	Glypican 3/GPC3 Protein, Canine, Recombinant (His) glypican 3	Canine	HEK293 Cells
	Glypican 3/GPC3 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.07 kDa and the accession number is A0A8C0TMC5.
TMPY-06820	Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His) glypican 3	Cynomolgus	HEK293 Cells
	Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.64 kDa and the accession number is XP_005594665.1.
TMPY-05106	Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated SGB,GTR2-2,SDYS,DGSX,OCI-5,Glypican 3,SGBS,SGBS1,MX...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P51654-1.
TMPY-05805	Glypican 3/GPC3 Protein, Human, Recombinant (S495A, hFc) GTR2-2,SGBS,DGSX,SGBS1,OCI-5,SGB,MXR7,glypican 3,SD...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (S495A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 86.46 kDa and the accession number is I6QTG3.
TMPY-05806	Glypican 3/GPC3 Protein, Human, Recombinant (S495A, mFc) DGSX,SGBS,SGB,GTR2-2,SGBS1,Glypican 3,OCI-5,MXR7,SD...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (S495A, mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 86.11 kDa and the accession number is I6QTG3.
TMPY-06877	Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated DGSX,SDYS,GTR2-2,SGBS,Glypican 3,OCI-5,SGBS1,SGB,MX...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 64.05 kDa and the accession number is P51654-1.
TMPK-01081	Glypican 2/GPC2 Protein, Mouse, Recombinant (His) Cerebroglycan,2410016G05Rik,GPC2,Glypican-2	Mouse	HEK293 Cells
	Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
TMPH-03279	DPP4/CD26 Protein, Rat, Recombinant (His & SUMO) Dpp4,Dipeptidyl peptidase IV,DPP IV,CD26,Dipeptidyl peptidas...	Rat	E. coli
	Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular ...
TMPY-01412	Glypican 5 Protein, Human, Recombinant (His) glypican 5	Human	Baculovirus Insect Cells
	Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control of cell division and growth regulation. So far, six members (Glypican-1/GPC1, Glypican-2/GPC2, Glypican-3/GPC3, Glypican-4/GPC4, Glypican-5/GPC5, Glypican-6/GPC6) of this family are known in the vertebrates. In the adult, Glypican-5 is primarily expressed in the brain. It is als...

重组蛋白

GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00337

Species: Human

Expression System: HEK293 Cells

GPC3 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-01423

Species: Rhesus

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01283

Species: Human

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00502

Species: Mouse

Expression System: Baculovirus Insect Cells

GPC3 Protein-VLP, Human, Recombinant

Cat.No: TMPK-00336

Species: Human

Expression System: E. coli

GPC3 Protein-VLP, Human, Recombinant (aa 438-554)

Cat.No: TMPK-00337

Species: Human

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03307

Species: Rat

Expression System: P. pastoris (Yeast)

Glypican 3/GPC3 Protein, Canine, Recombinant (His)

Cat.No: TMPY-06751

Species: Canine

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06820

Species: Cynomolgus

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05106

Species: Human

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (S495A, hFc)

Cat.No: TMPY-05805

Species: Human

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (S495A, mFc)

Cat.No: TMPY-05806

Species: Human

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06877

Species: Human

Expression System: HEK293 Cells

Glypican 2/GPC2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01081

Species: Mouse

Expression System: HEK293 Cells

DPP4/CD26 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03279

Species: Rat

Expression System: E. coli

Glypican 5 Protein, Human, Recombinant (His)

Cat.No: TMPY-01412

Species: Human

Expression System: Baculovirus Insect Cells

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