Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15403 |
GNE-618
|
NAMPT | Metabolism |
GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity. |