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Cat. No. Product Name Target Signaling Pathways
T1998 CHS-828

CHS 828,GMX1778

Apoptosis; NAMPT Apoptosis; Metabolism
CHS-828 (GMX1778) 是一种竞争性的烟酰胺磷酸化转移酶抑制剂,IC50值 <25 nM。它通过降低细胞中的 NAD+水平发挥细胞毒性作用,具有抗癌活性。
T71359 ArgTX-93 TFA

ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.
T71361 CHS-828 nicotinate

CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. CHS 828 showed a synergistic effect with melphalan in 67%, ...

化合物

CHS-828
Cat.No: T1998
Synonym: CHS 828,GMX1778
Target: Apoptosis, NAMPT
ArgTX-93 TFA
Cat.No: T71359
Synonym:
Target:
CHS-828 nicotinate
Cat.No: T71361
Synonym:
Target:
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