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7

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
T4473 Ibiglustat

Venglustat,SAR402671,GZ402671

Transferase Metabolism
Ibiglustat (GZ402671) 是一种可透过血脑屏障的、具有口服活性的葡萄糖神经酰胺合成酶(GCS)抑制剂。它可用于戈谢病 3 型、法布瑞氏症、与 GBA 突变相关的帕金森病、GM2 神经节苷脂病和常染色体显性多囊肾病的研究。
T41074 MB-VC-MGBA

MB-VC-MGBA is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), utilizing the minor-groove-binding DNA-alkylating agent (MGBA), connected through the ADC linker MB-VC.
T78573 Glucocerebrosidase

GCase,Glucosylceramidase

Endogenous Metabolite Metabolism
Glucocerebrosidase (Glucosylceramidase; GBA) 是溶酶体内的酶,负责催化GC中的β-糖苷键裂解,从而生成葡萄糖和神经酰胺。
TP2173 γ-Glu-Phe TFA (7432-24-8 free base)

γ-Glutamylphenylalanine TFA,γ-Glu-Phe TFA

Others Others
γ-Glu-Phe TFA is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). It enhances the umami intensity of commercial soy sauce and model chicken broth.
T39105 Ibiglustat succinate

GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate

Ibiglustat (Venglustat) succinate is an orally active, brain-penetrant inhibitor of glucosylceramide synthase (GCS). It is utilized in the investigation of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
T73635 γ-Glu-Phe TFA

γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) 是由解淀粉芽孢杆菌 (GBA) 和米曲霉 (GAO) 合成的。γ-Glu-Phe TFA 或酶后反应混合物可增强商业酱油和模型鸡汤的鲜味强度。
TP1001 γ-Glu-Phe

γ-Glutamylphenylalanine

γ-Glu-Phe (γ-Glutamylphenylalanine) is a γ-3 glutamyl dipeptide found in sourdough.it is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commerc

化合物

Ibiglustat
Cat.No: T4473
Synonym: Venglustat,SAR402671,GZ402671
Target: Transferase
MB-VC-MGBA
Cat.No: T41074
Synonym:
Target:
Glucocerebrosidase
Cat.No: T78573
Synonym: GCase,Glucosylceramidase
Target: Endogenous Metabolite
γ-Glu-Phe TFA (7432-24-8 free base)
Cat.No: TP2173
Synonym: γ-Glutamylphenylalanine TFA,γ-Glu-Phe TFA
Target: Others
Ibiglustat succinate
Cat.No: T39105
Synonym: GZ402671succinate,Venglustat succinate,Ibiglustat succinate,SAR402671succinate
Target:
γ-Glu-Phe TFA
Cat.No: T73635
Synonym:
Target:
γ-Glu-Phe
Cat.No: TP1001
Synonym: γ-Glutamylphenylalanine
Target:
Cat. No. Product Name Target Signaling Pathways
T4927 4-Guanidinobutanoic acid

4-GBA,4-胍基丁酸,4-Guanidinobutyric acid

Endogenous Metabolite Metabolism
4-Guanidinobutanoic acid (4-GBA) 是一种 L-精氨酸代谢物,已用于肠道转运研究。 它已专门用于人质子偶联氨基酸转运蛋白 hPAT1。

天然产物

4-Guanidinobutanoic acid
Cat.No: T4927
Synonym: 4-GBA,4-胍基丁酸,4-Guanidinobutyric acid
Target: Endogenous Metabolite
TargetMol Loading
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