Cat. No. | Product Name | Target | Signaling Pathways |
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T77633 |
G43
G 43,G-43 |
Antibacterial; Transferase | Metabolism; Microbiology/Virology |
G43 是一种有效的选择性 glucosyltransferase 抑制剂,对 GtfB 和 GtfC 具有抑制作用,Kd 值分别为3.7 μM和46.9 nM。G43 在体内外具有抗变形链球菌 (S. mutans)活性,可用于研究龋齿。 | |||
T37178 |
Norhyodeoxycholic Acid
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Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3 |1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon ... | |||
T36215 |
17R(18S)-EpETE
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17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ... |