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Cat. No. Product Name Target Signaling Pathways
T63234 Factor XI-IN-1

Factor XI-IN-1factor XI 活化 (factor XI activation) 抑制剂(EC50: 25.14 nM)。
T79847 Frunexian

EP-7041

Factor Xa Metabolism
Frunexian (EP-7041) 为针对 Factor XIa 的选择性有效凝血因子 XI/活化因子 XI 抑制剂,展现抗血栓活性,且在大鼠肠系膜动脉穿刺模型中显示出无出血倾向。此化合物亦可应用于体外膜氧合(ECMO)的研究领域。
T36461 CAY10748

CAY10748

CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, respectively, in a reporter assay). It induces phosphorylation of STING at the serine in position 366, as well as phosphorylation of TBK1 and IFN regulatory factor 3 (IRF3), indicating activation of the STING-TBK1-IRF3 signaling pathway. CAY10748 increases the secretion of IFN-β an...

化合物

Factor XI-IN-1
Cat.No: T63234
Synonym:
Target:
Frunexian
Cat.No: T79847
Synonym: EP-7041
Target: Factor Xa
CAY10748
Cat.No: T36461
Synonym: CAY10748
Target:
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