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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11327 |
FR 167653
FR 167653 sulfate |
p38 MAPK | MAPK |
FR 167653 (FR 167653 sulfate) is effective in treating inflammation, relieving trauma and ischemia-reperfusion injury in vivo. FR 167653 , an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. | |||
T69268 |
BGC-638
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BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors. | |||
T11327L | FR 167653 free base | Others | Others |
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MA |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00147 |
FOLR1 Protein, Human, Recombinant (hFc)
Folate receptor 1,Folate receptor,Folate receptor alpha,FOLR... |
Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPK-00150 |
FOLR1 Protein, Human, Recombinant (His & Avi)
Folate receptor 1,Folbp1,Folate receptor alpha,FR-a... |
Human | HEK293 Cells |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t... | |||
TMPJ-00148 |
FOLR1 Protein, Rhesus macaque, Recombinant (His)
FR-alpha,Adult folate-binding protein,Ovarian tumor... |
Rhesus | HEK293 Cells |
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60. |