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Cat. No. Product Name Target Signaling Pathways
T22081 FBPase-1 inhibitor-1

Fructose 1,6-bisphosphatase-1 Inhibitor

Others Others
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) 是一种fructose-1,6-bisphosphatase (FBPase-1)的变构抑制剂。
T60312 FBPase-IN-1

FBPase-IN-1 is a powerful inhibitor of Fructose-1,6-bisphosphatase (FBPase), a key enzyme involved in Type 2 diabetes (T2D) research. It exhibits an impressive IC50 value of 0.22 μM. Aside from its potency, FBPase-IN-1 also demonstrates the ability to effectively lower blood glucose levels and improve glucose tolerance. Its mechanism of action involves covalently modifying the C128 site, thereby influencing the N125-S124-S123 allosteric pathway of FBPase, ultimately impacting its catalytic activ...
T60294 FBPase-IN-2

FBPase-IN-2 (HS36) 是一种有效的果糖-1,6-二磷酸酶 (FBPase) 共价抑制剂,IC50值为 0.15 μM。FBPase-IN-2 可减少肝细胞内葡萄糖的产生,可用于二型糖尿病的研究。
T16009L Managlinat dialanetil

MB06322,MB 6322,CS-917

Phosphatase Metabolism
Managlinat dialanetil (MB06322) 是一种可口服且具有有效性的 fructose 1,6-bisphosphatase (FBPase) 抑制剂,具有降糖活性,可用于研究 2 型糖尿病。
T16020 MB05032

Others Others
MB05032 targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase), which is a special and efficacious inhibitor of GNG.
T16017 MB-07803

Others Others
MB07803 is an orally available prodrug of an effective, noncompetitive inhibitor of fructose 1,6-bisphosphatase (FBPase) (EC50: 140 nM and t1/2 of 7.6±2.9 h).
T16009 (Rac)-Managlinat dialanetil

CS-917,(Rac)-MB06322,MB06322,(Rac)-CS-917

Others; DHFR Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
(Rac)-Managlinat dialanetil ((Rac)-MB06322) 是 Managlinat dialanetil 的外消旋体,Managlinat dialanetil 是一种可口服且具有有效性的 fructose 1,6-bisphosphatase (FBPase) 抑制剂,可用于研究 2 型糖尿病。

化合物

FBPase-1 inhibitor-1
Cat.No: T22081
Synonym: Fructose 1,6-bisphosphatase-1 Inhibitor
Target: Others
FBPase-IN-1
Cat.No: T60312
Synonym:
Target:
FBPase-IN-2
Cat.No: T60294
Synonym:
Target:
Managlinat dialanetil
Cat.No: T16009L
Synonym: MB06322,MB 6322,CS-917
Target: Phosphatase
MB05032
Cat.No: T16020
Synonym:
Target: Others
MB-07803
Cat.No: T16017
Synonym:
Target: Others
(Rac)-Managlinat dialanetil
Cat.No: T16009
Synonym: CS-917,(Rac)-MB06322,MB06322,(Rac)-CS-917
Target: Others, DHFR
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