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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T64357 |
FA16
FA 16,FA-16 |
Ferroptosis | Apoptosis |
FA16 是一种选择性、代谢稳定的铁死亡 (ferroptosis) 诱导剂 ,IC50 值为1.26 μM。FA16 是 2-(三氟甲基) 苯并咪唑的衍生物。FA16 对胱氨酸/谷氨酸反转运蛋白 (system Xc-) 介导了细胞内谷氨酸和细胞外胱氨酸的交换有抑制作用。FA16 在 HepG2 异种移植瘤模型中显著抑制肿瘤生长。 | |||
T69276 | KFA1982 | ||
KFA1982 is a novel and potent factor Xa inhibitor. | |||
T13917 |
tCFA15
|
Others | Others |
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation. | |||
T62856 |
FFA1 agonist-1
|
||
FFA1 agonist-1 (Compound 17a) 是一种口服具有活力的脂肪酸受体(FFA1)激动剂 (EC50: 0.75 μM)。FFA1 agonist-1 能够用于研究 Ⅱ 型糖尿病。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00942 |
DLK1 Protein, Mouse, Recombinant (His)
DLK1,DLK,pG2,secredeltin,ZOG,Pref1,DLK- |
Mouse | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q09163-1. | |||
TMPK-00922 |
DLK1 Protein, Human, Recombinant (aa 24-303, His)
FA1,Pref1,DLK1,pG2,DLK,s... |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (aa 24-303, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is P8037... | |||
TMPK-00921 |
DLK1 Protein, Human, Recombinant (hFc)
DLK1,FA1,pG2,ZOG,secredeltin,DLK,... |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 56.58 kDa and the accession number is P80370-1. | |||
TMPK-01274 |
DLK1 Protein, Cynomolgus, Recombinant (His)
FA1,DLK-1,secredeltin,DLK1 |
Cynomolgus | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.26 kDa and the accession number is A0A2K5TMQ6... | |||
TMPY-02544 |
FANCA Protein, Human, Recombinant (His)
FA-H,FA1,FAA,FA... |
Human | Baculovirus Insect Cells |
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2. | |||
TMPH-02503 |
DEFA1 Protein, Mouse, Recombinant (GST & His)
HP-1,HNP-1,Defensin, alpha 1,DE |
Mouse | E. coli |
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477. | |||
TMPH-02576 |
TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation. | |||
TMPK-01201 |
BPIFA1/LUNX Protein, Human, Recombinant
Lung-specific protein X,BPI fold-containing family ... |
Human | E. coli |
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity. BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases. | |||
TMPH-01772 |
DEFA1 Protein, Human, Recombinant (GST)
MRS,HP1,HP-1,DEFA1,DEF |
Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665. |