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Targets Recommended: Ferroptosis

4

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T64357 FA16

FA 16,FA-16

Ferroptosis Apoptosis
FA16 是一种选择性、代谢稳定的铁死亡 (ferroptosis) 诱导剂 ,IC50 值为1.26 μM。FA16 是 2-(三氟甲基) 苯并咪唑的衍生物。FA16 对胱氨酸/谷氨酸反转运蛋白 (system Xc-) 介导了细胞内谷氨酸和细胞外胱氨酸的交换有抑制作用。FA16 在 HepG2 异种移植瘤模型中显著抑制肿瘤生长。
T69276 KFA1982

KFA1982 is a novel and potent factor Xa inhibitor.
T13917 tCFA15

Others Others
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.
T62856 FFA1 agonist-1

FFA1 agonist-1 (Compound 17a) 是一种口服具有活力的脂肪酸受体(FFA1)激动剂 (EC50: 0.75 μM)。FFA1 agonist-1 能够用于研究 Ⅱ 型糖尿病。

化合物

FA16
Cat.No: T64357
Synonym: FA 16,FA-16
Target: Ferroptosis
KFA1982
Cat.No: T69276
Synonym:
Target:
tCFA15
Cat.No: T13917
Synonym:
Target: Others
FFA1 agonist-1
Cat.No: T62856
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-00942 DLK1 Protein, Mouse, Recombinant (His)

DLK1,DLK,pG2,secredeltin,ZOG,Pref1,DLK-

Mouse HEK293 Cells
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q09163-1.
TMPK-00922 DLK1 Protein, Human, Recombinant (aa 24-303, His)

FA1,Pref1,DLK1,pG2,DLK,s...

Human HEK293 Cells
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (aa 24-303, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is P8037...
TMPK-00921 DLK1 Protein, Human, Recombinant (hFc)

DLK1,FA1,pG2,ZOG,secredeltin,DLK,...

Human HEK293 Cells
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 56.58 kDa and the accession number is P80370-1.
TMPK-01274 DLK1 Protein, Cynomolgus, Recombinant (His)

FA1,DLK-1,secredeltin,DLK1

Cynomolgus HEK293 Cells
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.26 kDa and the accession number is A0A2K5TMQ6...
TMPY-02544 FANCA Protein, Human, Recombinant (His)

FA-H,FA1,FAA,FA...

Human Baculovirus Insect Cells
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IκB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2.
TMPH-02503 DEFA1 Protein, Mouse, Recombinant (GST & His)

HP-1,HNP-1,Defensin, alpha 1,DE

Mouse E. coli
Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477.
TMPH-02576 TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation.
TMPK-01201 BPIFA1/LUNX Protein, Human, Recombinant

Lung-specific protein X,BPI fold-containing family ...

Human E. coli
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity. BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases.
TMPH-01772 DEFA1 Protein, Human, Recombinant (GST)

MRS,HP1,HP-1,DEFA1,DEF

Human E. coli
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665.

重组蛋白

DLK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00942
Species: Mouse
Expression System: HEK293 Cells
DLK1 Protein, Human, Recombinant (aa 24-303, His)
Cat.No: TMPK-00922
Species: Human
Expression System: HEK293 Cells
DLK1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00921
Species: Human
Expression System: HEK293 Cells
DLK1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01274
Species: Cynomolgus
Expression System: HEK293 Cells
FANCA Protein, Human, Recombinant (His)
Cat.No: TMPY-02544
Species: Human
Expression System: Baculovirus Insect Cells
DEFA1 Protein, Mouse, Recombinant (GST & His)
Cat.No: TMPH-02503
Species: Mouse
Expression System: E. coli
TAFA1/FAM19A1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02576
Species: Mouse
Expression System: E. coli
BPIFA1/LUNX Protein, Human, Recombinant
Cat.No: TMPK-01201
Species: Human
Expression System: E. coli
DEFA1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01772
Species: Human
Expression System: E. coli
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