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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37445 |
Etanercept
|
TNF | Apoptosis |
Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TNF biologically inactive. Etanercept has demonstrated efficacy in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01382 |
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)
p75TNFR,p75TBPII,CD120b,TNF-R75,TNFR1B,TNFR2,TNF-R2,Etan... |
Cynomolgus | HEK293 Cells |
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects o... | |||
TMPJ-00618 |
TNF RII Protein, Rhesus macaque, Recombinant (hFc)
Tnfrsf1b,Tumor necrosis factor receptor superfamily member 1... |
Rhesus | HEK293 Cells |
TNF RII Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-80 KDa and the accession number is F7EAF8. | |||
TMPJ-00296 |
TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated
Tumor necrosis factor receptor superfamily member 1b,Tnfrsf1... |
Mouse | HEK293 Cells |
TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-50 KDa and the accession number is Q545P4. | |||
TMPY-01697 |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
Tnfr-1,TNFR80,TNF-R-II,TNF-αR2,tumor necrosis factor recepto... |
Mouse | HEK293 Cells |
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119. |