Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4451L |
Estramustine phosphate
LS 299,NSC 89199,NSC-89199,LS-299,LS299 |
||
Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties. | |||
T4451 |
Estramustine phosphate sodium
Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠 |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物,是一种具有口服活性抗微管化疗剂,通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡,可研究前列腺癌。 | |||
T20681 |
Estramustine
NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275 |
Microtubule Associated | Cytoskeletal Signaling |
Estramustine (LEO-275) 是一种与雌二醇相连的氮芥,通常为磷酸盐。它已被用于治疗前列腺肿瘤;还具有防辐射功能。它被前列腺细胞选择性吸收,并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。 | |||
T25391 |
Estromustine
Leo-271 f,Leo 271 f,Leo271 f |
||
Estromustine is a major active metabolite of the cystotatic estrogen and nitrogen mustard alkylating antineoplastic agent estramustine phosphate, used in the therapy of prostate cancer. |