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Cat. No. Product Name Target Signaling Pathways
T4314 EPZ020411

EPZ020411 2HCl

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411是一种特异性有效的 PRMT6 抑制剂, IC50 为 10 nM,比作用于 PRMT1 和 PRMT8 的选择性高10倍多。
T22325 EPZ020411 hydrochloride

EPZ020411 HCl

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411 hydrochloride 是一种选择性的和有效的 PRMT6抑制剂,IC50=10 nM。
T4334 EPZ020411 2HCl (1700663-41-7(free base))

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411 2HCl (1700663-41-7(free base)) 是一种有效且特异性的小分子 PRMT6 抑制剂 (IC50=10 nM)。
T69922 EPZ020411 HCl

EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 arginine methylation and improves the cytotoxic activity of radiotherapy against GSC brain tumor xenografts.
T71899 Verubecestat TFA

Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.

化合物

EPZ020411
Cat.No: T4314
Synonym: EPZ020411 2HCl
Target: Histone Methyltransferase
EPZ020411 hydrochloride
Cat.No: T22325
Synonym: EPZ020411 HCl
Target: Histone Methyltransferase
EPZ020411 2HCl (1700663-41-7(free base))
Cat.No: T4334
Synonym:
Target: Histone Methyltransferase
EPZ020411 HCl
Cat.No: T69922
Synonym:
Target:
Verubecestat TFA
Cat.No: T71899
Synonym:
Target:
TargetMol Loading
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