Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22325 |
EPZ020411 hydrochloride
EPZ020411 HCl |
Histone Methyltransferase | Chromatin/Epigenetic |
EPZ020411 hydrochloride 是一种选择性的和有效的 PRMT6抑制剂,IC50=10 nM。 | |||
T71899 |
Verubecestat TFA
|
||
Verubecestat TFA, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat TFA is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat TFA reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. |