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Cat. No. Product Name Target Signaling Pathways
T22325 EPZ020411 hydrochloride

EPZ020411 HCl

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411 hydrochloride 是一种选择性的和有效的 PRMT6抑制剂,IC50=10 nM。
T4314 EPZ020411

EPZ020411 2HCl

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411是一种特异性有效的 PRMT6 抑制剂, IC50 为 10 nM,比作用于 PRMT1 和 PRMT8 的选择性高10倍多。
T4334 EPZ020411 2HCl (1700663-41-7(free base))

Histone Methyltransferase Chromatin/Epigenetic
EPZ020411 2HCl (1700663-41-7(free base)) 是一种有效且特异性的小分子 PRMT6 抑制剂 (IC50=10 nM)。
T71899 Verubecestat TFA

Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.
T69922 EPZ020411 HCl

EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 arginine methylation and improves the cytotoxic activity of radiotherapy against GSC brain tumor xenografts.

化合物

EPZ020411 hydrochloride
Cat.No: T22325
Synonym: EPZ020411 HCl
Target: Histone Methyltransferase
EPZ020411
Cat.No: T4314
Synonym: EPZ020411 2HCl
Target: Histone Methyltransferase
EPZ020411 2HCl (1700663-41-7(free base))
Cat.No: T4334
Synonym:
Target: Histone Methyltransferase
Verubecestat TFA
Cat.No: T71899
Synonym:
Target:
EPZ020411 HCl
Cat.No: T69922
Synonym:
Target:
TargetMol Loading
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