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Cat. No. | Product Name | Target | Signaling Pathways |
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T38759 |
ONO-8430506
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PDE | Metabolism |
ONO-8430506 是一种可口服的、具有有效性的 autotaxin (ATX)/ENPP2 抑制剂( IC90 :100 nM),能够抑制小鼠血浆中 ATX 活性。 | |||
T37431 |
ENPP1 Inhibitor C
ENPP1 Inhibitor C |
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ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50 = 0.26 μM in a cell-free assay).1 It is selective for ENPP1 over ENPP2-7 at 10 μM. ENPP1 inhibitor C decreases ENPP1 activity in MDA-MB-231 human breast and C6 rat glioma cancer cells when used at a concentration of 10 μM. |1. Kawaguchi, M., Han, X., Hisada, T., et al. Development of an ENPP1 fluorescence probe for inhibitor screening, cellular imaging, and prognostic assessment of malignant brea... | |||
T63325 |
ATX inhibitor 9
|
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ATX inhibitor 9 是增稠的杂芳基衍生物化合物,也是 ATX 的有效抑制剂。其中 Autotaxin (ATX),也称为 ENPP2,是一种主要在肺癌细胞、支气管上皮细胞和肺泡巨噬细胞中高度表达的分泌酶。ATX inhibitor 9 对癌症或纤维退行性疾病具有研究潜力。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-00463 |
ENPP2 Protein, Cynomolgus, Recombinant (His)
ENPP2,ectonucleotide pyrophosphatase/phosp... |
Cynomolgus | HEK293 Cells |
ENPP2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is XP_005564040.1. | |||
TMPY-02778 |
ENPP2 Protein, Human, Recombinant (His)
ATX,ectonucleotide pyrophosphatase/phosphodiesterase 2 |
Human | HEK293 Cells |
ENPP2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is AAH34961.1. | |||
TMPY-02055 |
ENPP2 Protein, Mouse, Recombinant (His)
PD-Ialpha,Pdnp2,ectonucleotide pyrophosphatase/phos... |
Mouse | HEK293 Cells |
ENPP2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 96 kDa and the accession number is Q9R1E6-1. |