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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35593 |
Semapimod tetrahydrochloride
CPSI-2364 tetrahydrochloride |
TLR; MAPK | Immunology/Inflammation; MAPK |
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂,干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导,抑制 TNF-α、IL-1β 和 IL-6,可用于研究克罗恩病和其他炎症。 | |||
T79304 |
Semapimod
CPSI-2364,CNI-1493 free base |
||
Semapimod是一种抑制促炎细胞因子产生的化合物,具有抑制TNF-α、IL-1β和IL-6功能。它通过抑制巨噬细胞的p38 MAPK以及一氧化氮的生成发挥作用,并且能够抑制TLR4信号传导(IC50约为0.3 μM)。Semapimod对于治疗各类炎症和自身免疫性疾病显示出潜在效用。 | |||
T34610 |
Semapimod hydrochloride dihydrate
|
||
Semapimod hydrochloride dihydrate is a biochemical. | |||
T34610L |
Semapimod mesylate
Semapimod tetramesylate |
||
Semapimod mesylate is a biochemical. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03700 |
S100A11 Protein, Mouse, Recombinant (His)
Emap1,S100a14,S100 calcium binding protein A11,S100c,S100A11... |
Mouse | E. coli |
S100A11 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.6 kDa and the accession number is P50543. |