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Cat. No. Product Name Target Signaling Pathways
TP1922L1 ELA-11 (human) acetate(1784687-32-6 free base)

Apelin receptor; Arrestin GPCR/G Protein
ELA-11 (human) acetate(1784687-32-6 free base)是亲和力 apelin 受体激动剂 (Ki = 14 nM)。 ELA-32 的生物活性片段。在体外抑制毛喉素诱导的 cAMP 产生并刺激 β-arrestin 募集。
TP2097 ELA-32(human)

ELA-32 (human)

Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. Also potentiates the T
TP1923 Elabela(19-32)

ELA-14 (human)

Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.
T76052 ELA-32(human) TFA

ELA-32(human) TFA is a potent, high affinityapelin receptoragonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
T76053 ELA-11(human) TFA

ELA-11(human) TFA is a high affinityapelin receptoragonist (Ki=14 nM). ELA-11(human) TFA is a bioactive fragment of ELA-32. ELA-11(human) TFA inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.

化合物

ELA-11 (human) acetate(1784687-32-6 free base)
Cat.No: TP1922L1
Synonym:
Target: Apelin receptor, Arrestin
ELA-32(human)
Cat.No: TP2097
Synonym: ELA-32 (human)
Target:
Elabela(19-32)
Cat.No: TP1923
Synonym: ELA-14 (human)
Target:
ELA-32(human) TFA
Cat.No: T76052
Synonym:
Target:
ELA-11(human) TFA
Cat.No: T76053
Synonym:
Target:
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