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Cat. No.	Product Name	Target	Signaling Pathways
TP1922L1	ELA-11 (human) acetate(1784687-32-6 free base)	Apelin receptor; Arrestin	GPCR/G Protein
	ELA-11 (human) acetate(1784687-32-6 free base)是亲和力 apelin 受体激动剂 (Ki = 14 nM)。 ELA-32 的生物活性片段。在体外抑制毛喉素诱导的 cAMP 产生并刺激 β-arrestin 募集。
TP2097	ELA-32(human) ELA-32 (human)
	Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. Also potentiates the T
TP1923	Elabela(19-32) ELA-14 (human)
	Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.
T76052	ELA-32(human) TFA
	ELA-32(human) TFA is a potent, high affinityapelin receptoragonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
T76053	ELA-11(human) TFA
	ELA-11(human) TFA is a high affinityapelin receptoragonist (Ki=14 nM). ELA-11(human) TFA is a bioactive fragment of ELA-32. ELA-11(human) TFA inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
TP1922	ELA-11(human) ELA-11 (human)
	High affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
TP2096	ELA-21 (human)
	High affinity apelin receptor agonist. Binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP produc
T76044	Elabela(19-32) TFA
	Elabela(19-32) TFA 是ELABELA（ELA）与apelin受体(APJ)结合的活性片段，能激活Gαi1和β-arrestin-2信号通路，EC50值分别为8.6 nM和166 nM。该化合物可诱导受体内在化，降低动脉压，并对心脏具有正性肌力作用。

化合物

ELA-11 (human) acetate(1784687-32-6 free base)

Cat.No: TP1922L1

Target: Apelin receptor, Arrestin

ELA-32(human)

Cat.No: TP2097

Synonym: ELA-32 (human)

Elabela(19-32)

Cat.No: TP1923

Synonym: ELA-14 (human)

ELA-32(human) TFA

Cat.No: T76052

ELA-11(human) TFA

Cat.No: T76053

ELA-11(human)

Cat.No: TP1922

Synonym: ELA-11 (human)

ELA-21 (human)

Cat.No: TP2096

Elabela(19-32) TFA

Cat.No: T76044

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