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Targets Recommended: MAPK

2

抑制剂 & 化合物

29

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T28141 Nek2-IN-5

NCL00017509

MAPK MAPK
Nek2-IN-5 (NCL00017509) 是一种具有有效性和选择性的 NIMA 相关激酶 2(Nek2)抑制剂。
T73287 Nek2-IN-6

Nek2-IN-6 是一种有效的 NIMA 相关激酶 2 (Nek2) 抑制剂。

化合物

Nek2-IN-5
Cat.No: T28141
Synonym: NCL00017509
Target: MAPK
Nek2-IN-6
Cat.No: T73287
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-00898 EphB3 Protein, Human, Recombinant (His)

EC 2.7.10.1,EPHB3,ETK2,EK2

Human HEK293 Cells
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is contributed to downregulation of EphB3 in CRC. EphB3 expression in tumor cells may be a useful prognostic indicator for patients with CRC.
TMPY-01501 Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H1N1 HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03452.
TMPY-06985 NGF Protein, Human, Recombinant (HEK293)

NGFB,神经生长因子,Beta-NGF,HSAN5,β-NGF,nerve growth factor (beta p...

Human HEK293 Cells
NGF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.8 kDa. and the accession number is P01138.
TMPY-04090 Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01191 CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)

IMD18,CD3 epsilon,T3E,CD3 ε,CD3e molecule, ε (CD3-TCR comple...

Human HEK293 Cells
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.2 kDa and the accession number is P07766.
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)

BAFF,THANK,BLYS,TNFSF20,CD257,tumor necros...

Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-04544 MEK2 Protein, Human, Recombinant (GST)

mitogen-activated protein kinase kinase 2,FLJ2<...

Human Baculovirus Insect Cells
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ...
TMPY-05719 SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 28.36 kDa and the accession number is A0A6G7K2L4.
TMPJ-00716 Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)

DAN Domain Family Member 4,Cerberus,Cerberus-Related Protein...

Human HEK293 Cells
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in respon...
TMPH-01683 Tau Protein, Human, Recombinant (HEK293, His)

Human HEK293 Cells
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the ...
TMPY-00549 Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H5N1 HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is B7NWR4.
TMPY-06314 MMP-10 Protein, Human, Recombinant (HEK293, His)

STMY2,matrix metallopeptidase 10,SL-2

Human HEK293 Cells
MMP-10 Protein, Human, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.38 kDa and the accession number is P09238.
TMPH-00743 PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)

E. coli HEK293 Cells
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes. In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG). In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG. Mediates magnesium influx to the cytosol by activation o...
TMPY-03840 Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa.
TMPY-03800 Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H7N9 HEK293 Cells
Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa.
TMPY-00595 Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His)

Harvey rat sarcoma viral oncogene homolog

H5N1 HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B7NWR4.
TMPY-05661 SARS-CoV-2 Spike S1 Protein (HEK293, His)

HEK293 Cells
SARS-CoV-2 Spike S1 Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The accession number is A0A6G7K2L4.
TMPJ-00386 ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated

Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...

Human HEK293 Cells
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate...
TMPJ-01163 CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

CTGF,Connective tissue growth factor

Human HEK293 Cells
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPY-04681 CHEK2 Protein, Human, Recombinant (GST)

CDS1,HuCds1,checkpoint kinase 2,hCds1,LFS2...

Human Baculovirus Insect Cells
CHEK2 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 88.1 kDa and the accession number is O96017-1.
TMPJ-01022 SUMO3 Protein, Human, Recombinant (HEK293, His)

SMT3 homolog 1,Smt3A,Small ubiquitin-related modifier 3,Ubiq...

Human HEK293 Cells
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and/or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collect...
TMPH-00343 Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)

Angiopoietin-1,ANG-1,ANGPT1

Canine HEK293 Cells
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells wi...
TMPY-02024 L-selectin Protein, Human, Recombinant (HEK293,His)

LECAM1,TQ1,CD62L,LYAM1,LSEL,LNHR,LAM1,selectin L,PL...

Human HEK293 Cells
L-selectin Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P14151-1.
TMPY-02167 Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)

DF,Adn,complement factor D (adipsin)

Mouse HEK293 Cells
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P03953-2.
TMPY-05683 SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.54 kDa and the accession number is A0A6G7K2L4.
TMPJ-00895 SCF Protein, Rat, Recombinant (HEK293, His)

steel factor,Mast cell growth factor,SLF,MGFSHEP7,SCFStem ce...

Rat HEK293 Cells
SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II...
TMPY-04435 CHEK2 Protein, Mouse, Recombinant (His & GST)

Rad53,CHK2,checkpoint kinase 2,Cds1,HUCDS1

Mouse Baculovirus Insect Cells
CHEK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89 kDa and the accession number is Q9Z265.
TMPY-05932 Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)

NA Protein

H1N1 HEK293 Cells
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0G3XQY1.

重组蛋白

EphB3 Protein, Human, Recombinant (His)
Cat.No: TMPK-00898
Species: Human
Expression System: HEK293 Cells
Influenza A H1N1 (A/Puerto Rico/8/1934) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-01501
Species: H1N1
Expression System: HEK293 Cells
NGF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-06985
Species: Human
Expression System: HEK293 Cells
Influenza A H7N9 (A/Shanghai/2/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-04090
Species: H7N9
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
CD3 epsilon/CD3e Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPY-01191
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-01920
Species: Human
Expression System: HEK293 Cells
MEK2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04544
Species: Human
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike RBD Protein (HEK293, Avi & His), Biotinylated
Cat.No: TMPY-05719
Species: SARS-CoV-2
Expression System: HEK293 Cells
Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-00716
Species: Human
Expression System: HEK293 Cells
Tau Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPH-01683
Species: Human
Expression System: HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-00549
Species: H5N1
Expression System: HEK293 Cells
MMP-10 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPY-06314
Species: Human
Expression System: HEK293 Cells
PhoP Protein, E. coli, Recombinant (HEK293, His & Myc)
Cat.No: TMPH-00743
Species: E. coli
Expression System: HEK293 Cells
Influenza A H7N9 (A/Pigeon/Shanghai/S1069/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-03840
Species: H7N9
Expression System: HEK293 Cells
Influenza A H7N9 (A/Shanghai/1/2013) Hemagglutinin/HA Protein (HEK293, His)
Cat.No: TMPY-03800
Species: H7N9
Expression System: HEK293 Cells
Influenza A H5N1 (A/common magpie/Hong Kong/5052/2007) Hemagglutinin/HA1 Protein (HEK293, His)
Cat.No: TMPY-00595
Species: H5N1
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (HEK293, His)
Cat.No: TMPY-05661
Species:
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Cat.No: TMPJ-00386
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01163
Species: Human
Expression System: HEK293 Cells
CHEK2 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04681
Species: Human
Expression System: Baculovirus Insect Cells
SUMO3 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01022
Species: Human
Expression System: HEK293 Cells
Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
Cat.No: TMPH-00343
Species: Canine
Expression System: HEK293 Cells
L-selectin Protein, Human, Recombinant (HEK293,His)
Cat.No: TMPY-02024
Species: Human
Expression System: HEK293 Cells
Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293)
Cat.No: TMPY-02167
Species: Mouse
Expression System: HEK293 Cells
SARS-CoV-2 Spike RBD Protein (HEK293, His), Biotinylated
Cat.No: TMPY-05683
Species: SARS-CoV-2
Expression System: HEK293 Cells
SCF Protein, Rat, Recombinant (HEK293, His)
Cat.No: TMPJ-00895
Species: Rat
Expression System: HEK293 Cells
CHEK2 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04435
Species: Mouse
Expression System: Baculovirus Insect Cells
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (HEK293, His)
Cat.No: TMPY-05932
Species: H1N1
Expression System: HEK293 Cells
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