Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16078 |
Mirk-IN-1
Dyrk1B/A-IN-1 |
Others | Others |
Mirk-IN-1 is an effective inhibitor of Dyrk1B(Mirk kianse) and Dyrk1A (IC50: 68±48 nM and 22±8 nM respectively). | |||
T11132 | DYRKs-IN-1 | DYRK | Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
DYRKs-IN-1 has antitumor activity. DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively. | |||
T62043 | Dyrk1A/B-IN-1 | ||
Dyrk1A/B-IN-1 (compound 3n) 是有效的、选择性的和细胞渗透性的DYRK1A 和DYRK1B 抑制剂。Dyrk1A/B-IN-1抑制DYRK1A 和DYRK1B 的Ki 分别为 67.8 nM 和 237.9 nM,IC50分别为 1.1 μM 和 0.8 μM。 | |||
T72242 |
DYRKs-IN-1 hydrochloride
|
||
DYRKs-IN-1 hydrochloride是一种有效的DYRKs(双特异性酪氨酸磷酸化调节激酶)抑制剂,对DYRK1A和DYRK1B的IC50分别为5 nM和8 nM,具有抗肿瘤活性。 |