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Cat. No. Product Name Target Signaling Pathways
T78126 Dothiepin

Dosulepin,Dothep

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dothiepin(Dosulepin; Dothep)是一种具备镇静/抗焦虑作用的抗抑郁药物。该化合物主要通过抑制去甲肾上腺素的再摄取,而非血清素,以增强去肾上腺素能神经传递。同时,Dothiepin作为组胺H1受体的拮抗剂,具备显著的镇痛活性,适用于治疗心因性面部疼痛、特发性纤维肌痛综合征或类风湿关节炎,并且不具有心脏毒性。
T69579 Dothiepin HCl

Dothiepin HCl is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking effects.

化合物

Dothiepin
Cat.No: T78126
Synonym: Dosulepin,Dothep
Target: Histamine Receptor
Dothiepin HCl
Cat.No: T69579
Synonym:
Target:
TargetMol Loading
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