Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1216 |
Diethylstilbestrol
Stilbestrol,己烯雌酚,DES |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Diethylstilbestrol (DES) 是一种非甾体雌性激素,能够用于更年期和绝经后的紊乱。 | |||
T31450 |
Diethylstilbestrol dipropionate
|
||
Diethylstilbestrol dipropionate can be used in estrogen therapy of relapsed prostate cancer. | |||
T14226 |
Amino-PEG11-amine
氨基-十二聚乙二醇-氨基 |
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG11-amine 是一种基于 PEG(12 个单位)的 PROTAC 接头,能够结合两种基于单乙基雌酚的配体,是制备用于乳腺癌内分泌治疗的更具选择性和活性的 ER 拮抗剂的替代策略。 | |||
T14223 | Amino-PEG10-amine | Others | Others |
Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1]. |