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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T36920	16α-hydroxy Dehydroepiandrosterone
	16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydro...
T26366L	Prasterone sulfate sodium hydrate Sodium dehydroepiandrosterone sulfate,Prasterone sulfate sodium salt dihydrate,5-Androsten-3β-ol-17-one sulfate sodium salt dihydrate
	Prasterone is an endogenous steroid hormone. Prasterone acts as an agonist at ERβ, NMDA, and σ1 receptors, a partial agonist at ERα and AR, and antagonist at GABA-A receptors. It displays a variety of biologocial activities, including enhancing working me
T8401	Efonidipine hydrochloride monoethanolate NZ-105 hydrochloride monoethanolate,依福地平,盐酸依福地平一乙醇盐	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) 是 T 型和 L 型钙离子通道双重阻断剂。
T73671	7β-Hydroxy-epi-androsterone
	7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) 是一种与ERβ结合的内源性雄激素衍生物，具有抗炎和神经保护特性。该化合物来源于dehydroepiandrosterone。
T73779	5β-Androstan-3β-ol-17-one
	5β-Androstan-3β-ol-17-one（3β-Etiocholanolone；5β-Epiandrosterone），为5β还原型类固醇，主要是脱氢表雄酮（DHEA）的关键代谢物之一。在C57BL/KsJ基因型糖尿病（db/db）小鼠中，该化合物显示出显著的降糖效果，并且具有对神经元的抑制活性。

化合物

16α-hydroxy Dehydroepiandrosterone

Cat.No: T36920

Synonym:

Target:

Prasterone sulfate sodium hydrate

Cat.No: T26366L

Synonym: Sodium dehydroepiandrosterone sulfate,Prasterone sulfate sodium salt dihydrate,5-Androsten-3β-ol-17-one sulfate sodium salt dihydrate

Target:

Efonidipine hydrochloride monoethanolate

Cat.No: T8401

Synonym: NZ-105 hydrochloride monoethanolate,依福地平,盐酸依福地平一乙醇盐

Target: Calcium Channel

7β-Hydroxy-epi-androsterone

Cat.No: T73671

Synonym:

Target:

5β-Androstan-3β-ol-17-one

Cat.No: T73779

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T26366	Dehydroepiandrosterone sulfate PB 005,PB005,Prasterone sulfate,DHEA sulfate,DHEAS,PB-005	Others	Others
	Dehydroepiandrosterone sulfate (PB-005) 影响神经元的迁移、树突的分枝和新突触的形成。
T0856	Dehydroisoandrosterone 3-acetate Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,醋酸去氢表雄酮,androstenolone acetate	Androgen Receptor	Endocrinology/Hormones
	Dehydroisoandrosterone 3-acetate (Prasterone acetate) 是一种雄性激素/雌性激素的前体物质，是一种由肾上腺皮质产生的主要 C19 类固醇，能够调节脊椎动物的攻击性行为。
T41329	Dehydroepiandrosterone sulfate sodium salt
	Dehydroepiandrosterone sulfate sodium salt 影响神经元的迁移、树突的分枝和新突触的形成。
T10048	17a-Hydroxypregnenolone	Endogenous Metabolite	Metabolism
	17a-Hydroxypregnenolone 是一种孕烷类固醇, 是形成脱氢表雄酮的激素原。