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Search Results for " drd2 "

Targets Recommended: Dopamine Receptor

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16392	ONC206	Dopamine Receptor	GPCR/G Protein; Neuroscience
	ONC206 是一种 ONC201 的类似物，是一种多巴胺 D2- 样受体 (DRD2/3/4) 的选择性拮抗剂，其拮抗作用在纳摩尔级别。它具有广谱抗肿瘤活性。
T9228	Propionylpromazine hydrochloride 盐酸丙酰丙嗪,Propiopromazine hydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Propionylpromazine hydrochloride (Propiopromazine hydrochloride) 是多巴胺受体 D2 (DRD2) 拮抗剂，可用于研究帕金森氏病。
T69513	(–)-IHCH7041
	(–)-IHCH7041 is a optical rotation negative isomer of IHCH7041. (–)-IHCH7041 is a DRD2 partial agonist. (–)-IHCH7041 showed EC50 = 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment. (–)-IHCH7041 exhibited a inhibition constant (Ki) of 22.44 nM binding affinity at DRD2. (–)-IHCH7041 has antidepressant properties and reverses cognitive impairment.
T69512	IHCH7041
	IHCH7041, also known as (+/-)-IHCH7041, is a DRD2 partial agonist. IHCH7041 contains two enantiomers: (-)-IHCH7041 and (+)-IHCH7041 (optical rotation negative and positive). (+/-)-IHCH7041 has CAS#2813335-29-2. Two isomers have CAS#2813335-07-6 (rotation negative) and 2813335-06-5 (rotation positive), respectively.

化合物

Cat.No: T16392

Target: Dopamine Receptor

Propionylpromazine hydrochloride

Cat.No: T9228

Synonym: 盐酸丙酰丙嗪,Propiopromazine hydrochloride

Target: Dopamine Receptor

Cat.No: T69513

Cat.No: T69512

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01201	DRD2 Protein, Human, Recombinant (His & Myc) Dopamine D2 receptor,D(2) dopamine recepto...	Human	E. coli
	Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
TMPH-01797	NR4A2 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. NR4A2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is P43354.
TMPH-02020	RGS17 Protein, Human, Recombinant (GST)	Human	E. coli
	Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins. R...

重组蛋白

DRD2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01201

Species: Human

Expression System: E. coli

NR4A2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01797

Species: Human

Expression System: P. pastoris (Yeast)

RGS17 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02020

Species: Human

Expression System: E. coli

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