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Targets Recommended: Proteasome

3

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TQ0038 Brensocatib

AZD7986,INS 1007

Proteasome Proteases/Proteasome; Ubiquitination
Brensocatib (AZD7986) 是一种二肽基肽酶 1 (DPP1) 抑制剂,在人,小鼠,大鼠,狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。
T27468 GSK2793660 HCl

GSK-2793660,GSK2793660,GSK 2793660

GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.
T71117 AZD5248

AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).

化合物

Brensocatib
Cat.No: TQ0038
Synonym: AZD7986,INS 1007
Target: Proteasome
GSK2793660 HCl
Cat.No: T27468
Synonym: GSK-2793660,GSK2793660,GSK 2793660
Target:
AZD5248
Cat.No: T71117
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00732 Cathepsin C Protein, Human, Recombinant (His)

DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON

Human HEK293 Cells
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c...
TMPY-01854 DPP10 Protein, Human, Recombinant (His)

DPPY,DPRP3,DPRP-3,DPL2,dipeptidyl-peptidase 1

Human HEK293 Cells
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP1 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally p...

重组蛋白

Cathepsin C Protein, Human, Recombinant (His)
Cat.No: TMPY-00732
Species: Human
Expression System: HEK293 Cells
DPP10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01854
Species: Human
Expression System: HEK293 Cells
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