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Cat. No. Product Name Species Expression System
TMPH-01207 DOCK8 Protein, Human, Recombinant (His)

DOCK8,Dedicator of cytokinesis protein

Human P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing c...
TMPH-02623 DOCK8 Protein, Mouse, Recombinant (His)

Dedicator of cytokinesis protein 8,DOCK

Mouse P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent...
TMPH-02622 DOCK8 Protein, Mouse, Recombinant (E. coli, His)

DOCK8,Dedicator of cytokinesis protein

Mouse E. coli
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent...

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DOCK8 Protein, Human, Recombinant (His)
Cat.No: TMPH-01207
Species: Human
Expression System: P. pastoris (Yeast)
DOCK8 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02623
Species: Mouse
Expression System: P. pastoris (Yeast)
DOCK8 Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02622
Species: Mouse
Expression System: E. coli
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