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Cat. No. | Product Name | Target | Signaling Pathways |
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T35626 |
AMP-Deoxynojirimycin
AMP-DNM |
Transferase; Glucosidase | Metabolism |
AMP-Deoxynojirimycin (AMP-DNM) 是一种有效的神经酰胺葡萄糖基转移酶和 GCase 2 抑制剂。AMP-Deoxynojirimycin 是一种有效的 GlcCer 生物合成抑制剂,可用于研究帕金森和糖尿病。 | |||
T13856 | (R)-DNMDP | Others | Others |
(R)-DNMDP is a potent and selective agent of cancer cell cytotoxic. | |||
T15147 |
DNMDP
|
Others | Others |
DNMDP is a phosphodiesterase 3A inhibitor with clear cell-selective cytotoxicity. DNMDP binding to PDE3A promotes interaction between PDE3A and Schlafen 12. | |||
T63859 |
DNMT3A-IN-1
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DNMT3A-IN-1 是选择性的、有效的 DNMT3A 抑制剂。 DNMT3A-IN-1 对 DNMT3A 表现出抑制活性,其 KI 的范围为 9.16-18.85 μM (AdoMet) 和 11.37-23.34 μM (poly dI-dC)。 | |||
T37903 |
Deoxynojirimycin Tetrabenzyl Ether
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Deoxynojirimycin (dNM) tetrabenzyl ether is an intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits α-glucosidase I and II. |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01254 |
DNM1 Protein, Human, Recombinant (His)
DNM,Dynamin,Dynamin-1,DNM1,Dynamin I |
Human | E. coli |
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. | |||
TMPH-01255 |
DNM1L Protein, Human, Recombinant (His & Myc)
Dynamin-like protein IV,Dynamin-related protein 1,DLP1,Dympl... |
Human | E. coli |
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. The specific recruitment at scission sites is mediated by membrane receptors like MFF, MIEF1 and MIEF2 for mitochondrial membranes. While the recruitment by the membrane receptors is GTP-dependent, the following hydrolysis... | |||
TMPY-01306 |
DNMT2 Protein, Human, Recombinant (GST)
PUMET,RNMT1,tRNA aspartic acid methyltransferase 1,MHSAIIP,<... |
Human | Baculovirus-Insect Cells |
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evolution and contain all of the signature motifs of DNA (cytosine-5)-methyltransferases. It contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S:-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide, and its structure... |