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Search Results for " dll3 "

Targets Recommended: Gamma-secretase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T76698	Rovalpituzumab	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Rovalpituzumab 是一种靶向 delta 样蛋白 3 (DLL3) 的人源化单克隆抗体。Rovalpituzumab 可用于合成抗体-活性分子偶联物 (ADC)。Rovalpituzumab 具有抗癌活性，可用于治疗小细胞肺癌 (SCLC)。
T76986	Tarlatamab
	Tarlatamab (AMG-757) 是一种双特异性 T 细胞接合剂 (BiTE) 抗体，靶向 delta 样配体 3 (DLL3)。DLL3 是在小细胞肺癌 (SCLC) 肿瘤中选择性表达的靶标，但在正常组织中表达很少。Tarlatamab 对人和非人灵长类动物 (NHP) 的 DLL3 的KD 分别为 0.64 nM 和 0.50 nM，对CD3的KD 分别为 14.9 nM 和 12 nM。Tarlatamab 是针对 DLL3 的一流 HLE BiTE 免疫肿瘤疗法，具有用于 SCLC 研究的潜力。

化合物

Rovalpituzumab

Cat.No: T76698

Synonym:

Target: Gamma-secretase

Species：

Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPK-00640	DLL3 Protein, Rhesus macaque, Recombinant (His) SCDO1delta3,Pudgy,δ3,SCDO1,SCDO1δ3	Rhesus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51 kDa and t...
TMPK-01208	DLL3 Protein, Human, Recombinant (His & Flag) Pudgy,SCDO1,DLL3,Delta3,SCDO1δ	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.30 kDa...
TMPK-00748	DLL3 Protein, Mouse, Recombinant (His) Delta3,Pudgy,SCDO1δ3,DLL3	Mouse	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.02 kDa and the acc...
TMPK-01206	DLL3 Protein, Human, Recombinant (His & Avi) DLL3,Pudgy,Delta3,δ3,SCD...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.20 kDa a...
TMPK-01209	DLL3 Protein, Human, Recombinant (His) Pudgy,SCDO1delta3,DLL3,SCDO1δ...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 50.4 kDa and the acce...
TMPK-01207	DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated Pudgy,δ3,SCDO1δ3,Delta3,SCDO1delt...	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
TMPK-00543	DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) DLL3,SCDO1δ3,SCDO1,Pudgy,Delta	Cynomolgus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.80...
TMPK-00542	DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) SCDO1,Delta3,SCDO1δ3,δ3,SCDO1delt...	Cynomolgus	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.21...
TMPK-01210	DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated DLL3,SCDO1δ3,SCDO1,Pudgy,δ3	Human	HEK293 Cells
	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted mo...
TMPH-02424	DLL3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	DLL3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50.6 kDa and the accession number is A0A2K5WSR4.