首页 工具
登录
全部产品 抑制剂&激动剂 化合物库 天然产物 技术服务 重组蛋白 会员中心 联系我们
购物车
抑制剂&激动剂 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架 DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道 代谢 微生物学 神经科学
化合物库 活性化合物库 •   通用已知活性库 •   上市状态分类 •   疾病类型分类 •   通路靶点分类 天然产物库 •   高通量筛选天然产物库 •   特色天然产物库 •   天然产物衍生物库 Fragment片段库 •   通用片段库 •   特色片段库 类药性化合物库 •   多样性核心库Part2 •   多样性核心库Part1 化合物库深度定制
技术服务 计算机辅助药物设计 •   虚拟筛选 实体化合物活性筛选 •   分子结合&互作检测 药物设计和结构优化 天然产物 试剂盒 Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails SYBR Green qPCR Master Mix (No ROX) 染料试剂 多肽产品 抗体抑制剂 PROTAC
重组蛋白 细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体 •   受体酪氨酸激酶 CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白 CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白
信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道
代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
活性化合物库 上市药物库 临床期小分子药物库 已知活性化合物库 FDA上市及药典收录分子库 抗癌药物库 抗病毒库 铁死亡化合物库
天然产物库 高通量筛选天然产物库 Ro5类药天然产物库 中药单体化合物库 糖类及苷类化合物库 稀有天然产物库 天然产物衍生物库 天然产物单体化合物库
Fragment片段库 高溶解性片段库 精选片段库 高溶解性多官能团片段化合物库 高溶解性卤化片段化合物库 药物片段库 Mini片段亲电杂环化合物库 高溶解性微型片段化合物库
类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
苯丙烷 生物碱 酚类 其他
植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
莲叶桐科 胡桃科 石杉科 桔梗科 百合科 忍冬科 漆树科
计算机辅助药物设计 虚拟筛选 分子对接 反向找靶 分子动力学模拟
基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
病毒蛋白 •   冠状病毒蛋白 •   流感病毒蛋白 荧光蛋白 其他蛋白

搜索结果

Search Results for " dkk1 "
Targets Recommended: Wnt/beta-catenin

2

抑制剂 & 化合物

12

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T1971 WAY-262611

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
WAY262611是一种 Wnt/β- 联蛋白激动剂，也是一种Dkk1的抑制剂。它能够增加骨形成速率，在 TCF- 荧光素酶测定实验中的EC50=0.63 μM。
T35551 Gallocyanine

Gallocyanine is a small molecule blue dye used to stain nuclei. It is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Gallocyanine can disrupt the interaction of Dkk1 with its receptor LRP5/6 (IC50 = 3 μM), thereby activating Wnt/β-catenin signaling. Modulation of the Dkk1-LRP5/6 interaction via gallocyanine has been shown to inhibit prostaglandin J2-induced tau phosphorylation at serine396 in primary cortical neurons in vitro.

化合物

WAY-262611
Cat.No: T1971
Synonym:
Target: Wnt/beta-catenin
Gallocyanine
Cat.No: T35551
Synonym:
Target:
Species：
Human (8)
Rhesus (2)
Mouse (1)
Rat (1)
Expression System：
HEK293 Cells (12)
Tag：
C-hFc-Avi (4)
C-His (3)
C-Avi-6xHis (1)
C-C-His (1)
C-hFc (1)
His (1)
mFc (1)
Cat. No. Product Name Species Expression System
TMPY-00775 DKK1 Protein, Human, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1,SK,D...

 Human HEK293 Cells
DKK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.22 kDa and the accession number is I1W660.
TMPY-04811 DKK1 Protein, Mouse, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1,mdkk...

 Mouse HEK293 Cells
DKK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.6 kDa and the accession number is O54908.
TMPK-00155 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)

hDkk-1,Dickkopf-1,Dkk

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPK-00157 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

hDkk-1,SK,Dkk1,Dickkopf-...

 Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 38.69 kDa and the accession number is O94907.
TMPK-00156 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)

Dickkopf-1,Dkk1,hDkk-

Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPY-01174 DKK1 Protein, Rhesus, Recombinant (N256Q, His)

dickkopf WNT signaling pathway inhibitor 1

 Rhesus HEK293 Cells
DKK1 Protein, Rhesus, Recombinant (N256Q, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.2 kDa and the accession number is XP_001098844.1.
TMPK-00158 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

hDkk1,Dkk1,Dickkopf-...

 Human HEK293 Cells
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 40.25 kDa and the accession number is O94907.
TMPY-05479 DKK1 Protein, Human, Recombinant (hFc)

dickkopf WNT signaling pathway inhibitor 1,DKK<...

 Human HEK293 Cells
DKK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.5 kDa and the accession number is I1W660.
TMPY-05797 DKK1 Protein, Rat, Recombinant (His)

dickkopf WNT signaling pathway inhibitor 1

 Rat HEK293 Cells
DKK1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.44 kDa and the accession number is A6I0Z0.
TMPJ-00156 DKK1 Protein, Human, Recombinant (Avi & His), Biotinylated

Dickkopf-1,Dickkopf-related protein 1,...

 Human HEK293 Cells
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, lim...
TMPY-01175 DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)

dickkopf WNT signaling pathway inhibitor 1

 Rhesus HEK293 Cells
DKK1 Protein, Rhesus, Recombinant (N256Q, mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 53.5 kDa and the accession number is XP_001098844.1.
TMPY-04144 Kremen-1 Protein, Human, Recombinant (His)

KREMEN,KRM1,kringle containing transmembrane protei...

 Human HEK293 Cells
KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The cell surface molecule KREMEN1 is an entry receptor for coxsackievirus A1 (CV-A10). Whereas loss of KREMEN1 renders cells resistant to CV-A10 infection, KREMEN1 overexpression enhances CV-A10 binding to the cell surface and increases susceptibility...

重组蛋白

DKK1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00775
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04811
Species: Mouse
Expression System: HEK293 Cells
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-00155
Species: Human
Expression System: HEK293 Cells
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00157
Species: Human
Expression System: HEK293 Cells
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-00156
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Rhesus, Recombinant (N256Q, His)
Cat.No: TMPY-01174
Species: Rhesus
Expression System: HEK293 Cells
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00158
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05479
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-05797
Species: Rat
Expression System: HEK293 Cells
DKK1 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00156
Species: Human
Expression System: HEK293 Cells
DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)
Cat.No: TMPY-01175
Species: Rhesus
Expression System: HEK293 Cells
Kremen-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04144
Species: Human
Expression System: HEK293 Cells
TargetMol®
关于我们 隐私声明 前沿资讯 相关条款
相关支持
联系我们 全球经销商 订购指南 技术支持
技术资源
产品目录 产品引用文献 信号通路 溶液计算器
订阅 TargetMol®
订阅以获得我们的产品更新和特惠活动!
获取我们的最新产品和特惠活动!
TargetMol®
相关支持
技术资源
我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4 沪公网安备 31010602006700号 沪公网安备 31010602006700号
联系我们
400-820-0310
service@tsbiochem.com
2881945090（终端用户）
2885109491（经销商） 

上海市静安区江场三路238号8楼