14
1
Cat. No. | Product Name | Target | Signaling Pathways |
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T60002 |
DC-S239
|
Histone Methyltransferase | Chromatin/Epigenetic |
DC-S239 (DC-S239) 是一种选择性的组蛋白甲基转移酶 SETD7 抑制剂 (IC50 = 4.59 μM),具有抗癌活性。 | |||
T37147 |
5'-O-DMT-N4-Ac-dC
5'-O-DMT-N4-Ac-dC |
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5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7) is a deoxynucleoside utilized in the synthesis of dodecyl phosphoramidite. Dodecyl phosphoramidite serves as a crucial precursor for dod-DNA production, which is amphiphilic DNA comprising dodecyl phosphotriester linkages and featuring an internal hydrophobic region[1][2]. | |||
T37137 |
5'-O-DMT-N4-Bz-2'-F-dC
5’-O-DMT-N4-Bz-2’-F-dC |
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5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects. | |||
T37138 |
5'-O-DMT-N4-Bz-5-Me-dC
5’-O-DMT-N4-Bz-5-Me-dC |
||
5’-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid. | |||
T37136 |
5'-O-DMT-N4-Ac-2'-F-dC
5’-O-DMT-N4-Ac-2’-F-dC |
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5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA. | |||
T10972 |
DC4
|
Others | Others |
DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors. | |||
T74972 | A2-Iso5-4DC19 | ||
A2-Iso5-4DC19 为类脂化合物,有效递送多核苷酸等物质至细胞内,作为高效载体。 | |||
T40783 |
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
N4-苯甲酰基-5′-O-(4,4′-二甲氧基三苯基)-2′-脱氧胞苷,5'-O-DMT-N4-Bz-dC |
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N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine, also known as 5'-O-DMT-N4-Bz-dC, is a chemical compound utilized in the synthesis of oligodeoxynucleotides that incorporate a 3'-S-phosphorothiolate (3'-PS) linkage. It is valuable in investigating enzyme-catalyzed cleavage mechanisms within DNA. | |||
TNU1226 |
5’-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite
|
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5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite is a Nucleoside Phosphoramidite. | |||
T19773 |
Diethyl bipy55'DC
|
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Diethyl bipy55'DC inhibits CP4H activity in cultured cells. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases. | |||
T39930 |
MS98
|
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MS98 is a highly effective and specific PROTAC AKT degrader compound that effectively targets and depletes total AKT (T-AKT) within cells, exhibiting a DC 50 value of 78 nM. This compound readily binds to AKT1, AKT2, and AKT3 with respective dissociation constants (Kd s) of 4 nM, 140 nM, and 8.1 nM. | |||
T63315 | IRAK4-IN-19 | ||
IRAK4-IN-19 是白介素 1 受体相关激酶 4 (IRAK4) 的有效抑制剂 (IC50: 4.3 nM)。IRAK4-IN-19 能够阻碍 THP 和 DC 细胞中 LPS 诱导的 IL23 产生,抑制关节炎模型大鼠的关节炎发展。IRAK4-IN-19 能够用于研究关节炎疾病。 | |||
T62950 | IRAK4-IN-18 | ||
IRAK4-IN-18 是一种白介素 1 受体相关激酶 4 (IRAK4) 的有效抑制剂 (IC50: 15 nM)。IRAK4-IN-18 能够抑制 THP 和 DC 细胞中 LPS 诱导的 IL23 产生,阻断关节炎模型大鼠的关节炎发展。IRAK4-IN-18 可用于研究关节炎疾病。 | |||
T37880 |
OPC-167832
|
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OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN3801 |
methoxyphenoxy]oxane-3,4,5-triol
Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside |
Others | Others |
Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. |