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Search Results for " cytosolic-activating factor "

Targets Recommended: Others

1

抑制剂 & 化合物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T37331	Pyrrophenone	Others	Others
	The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py...

化合物

Cat.No: T37331

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO) acpP,Cytosolic-activating factor,...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST) acpP,Fatty acid synthase acyl carrier protein,Acyl carrier p...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001.
TMPH-00572	ACP Protein, E. coli, Recombinant (His & SUMO) acpP,Fatty acid synthase acyl carrier protein,Cytosolic<...	E. coli	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His) Cytosolic-activating factor,Fatty...	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPJ-01054	PAFAHB Protein, Human, Recombinant (His) PAFAH Subunit Beta,PAF-AH 30 kDa Subunit,Platelet-Activa...	Human	E. coli
	Platelet-Activating Factor Acetylhydrolase IB Subunit β (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position.
TMPJ-00789	Flagellin Protein, Salmonella Typhimurium, Recombinant flaF,Phase 1-I flagellin,Flagellin,fliC,hag	Salmonella typhimurium	E. coli
	Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin is used as an effective systemic or mucosal adjuvant to stimulate the immune system. Flagellin is an agonist of Toll-like receptor 5 (TLR5), a pattern recognition receptor (PRR) of the innate immune system expressed on the basolateral surface of intestinal epithelial cells and o...
TMPY-04387	AKT2 Protein, Human, Recombinant (His & GST) RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt murine t...	Human	Baculovirus Insect Cells
	AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma...
TMPY-01187	Rac1 Protein, Human, Recombinant (GST) Rac-1,p21-Rac1,MIG5,ras-related C3 botulinum toxin substrate...	Human	Baculovirus Insect Cells
	RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for RAC1 gene. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, bind...
TMPH-02521	PYCARD Protein, Mouse, Recombinant (His & Myc) Pycard,PYD and CARD domain-containing protein,Apoptosis-asso...	Mouse	E. coli
	Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3. Involved ...

重组蛋白

ACP Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00572

Species: E. coli

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

PAFAHB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01054

Species: Human

Expression System: E. coli

Flagellin Protein, Salmonella Typhimurium, Recombinant

Cat.No: TMPJ-00789

Species: Salmonella typhimurium

Expression System: E. coli

AKT2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04387

Species: Human

Expression System: Baculovirus Insect Cells

Rac1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01187

Species: Human

Expression System: Baculovirus Insect Cells

PYCARD Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02521

Species: Mouse

Expression System: E. coli

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