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Targets Recommended: CXCR

2

抑制剂 & 化合物

1

化合物库

3

重组蛋白

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Cat. No. Product Name
L7600 趋化因子抑制剂库

59 compounds
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

趋化因子抑制剂库
Cat.No: L7600
Compounds: 59
Cat. No. Product Name Target Signaling Pathways
T5849 JMS-17-2

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
JMS-17-2 是选择性CX3CR1拮抗剂(IC50:0.32 nM),能够抑制乳腺癌细胞的转移和定植。
T39879 JMS-17-2 hydrochloride

JMS-17-2 hydrochloride, a highly potent and selective CX3CR1 antagonist with an IC 50 value of 0.32 nM, effectively impedes the metastatic seeding and colonization process of breast cancer cells.

化合物

JMS-17-2
Cat.No: T5849
Synonym:
Target: CXCR
JMS-17-2 hydrochloride
Cat.No: T39879
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00673 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)

CXC3,Cx3c,NTN,Fkn,C3Xkine,C-X3-C ...

Mouse HEK293 Cells
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM1...
TMPK-00721 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated

Neurotactin,CXC3C,ABCD-3,Fkn,Fractalkine,N...

Mouse HEK293 Cells
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.
TMPY-02550 Eotaxin/CCL11 Protein, Human, Recombinant (His)

SCYA11,chemokine (C-C motif) ligand 11

Human E. coli
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small ...

重组蛋白

CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00673
Species: Mouse
Expression System: HEK293 Cells
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00721
Species: Mouse
Expression System: HEK293 Cells
Eotaxin/CCL11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02550
Species: Human
Expression System: E. coli
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