Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1532 | Crenulatin | BCL; Caspase | Apoptosis; Proteases/Proteasome |
Crenulatin has dual- direction effects on apoptosis of cerebral microvascular endothelial cells, inhibitive effect in 25 mg/L and stimulative effect in 100 mg/L group, respectively; the mechanism is related to the alterations of Fas/Bcl-2 expression and caspase-3 activity. |