Cat. No. | Product Name | Target | Signaling Pathways |
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T8439 |
Clobenpropit dihydrobromide
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Apoptosis; Histamine Receptor | Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Clobenpropit dihydrobromide 是一种组胺H3R 拮抗剂/反向激动剂。它与 5-HT3 受体和 α2A/α2C 肾上腺素受体结合,对组胺H4受体起部分激动剂的作用,还能促进凋亡。 | |||
T19762 |
Clobenpropit 2HBr
VUF-9153,VUF 9153,Clobenpropit Dihydrobromide,VUF9153 |
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Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain. | |||
T38323 |
A-943931 (hydrochloride hydrate)
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A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.). 1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification of two potent and selective histamine H4 receptor antagonists with antipruritic activityFASEB J.23(S1)760.768-760.768(2009) |