Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0089 |
Cetirizine dihydrochloride
盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物,是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性,抑制过敏反应期间嗜酸性粒细胞趋化,可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。 | |||
T9084 |
Cetirizine Impurity B dihydrochloride
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride,西替利嗪杂质B二盐酸盐,西替利嗪杂质04 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Cetirizine Impurity B dihydrochloride (De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride) 是 Cetirizine dihydrochloride 的杂质。Cetirizine 是一种抗组胺剂,是口服有活力的、特异性 H1受体拮抗剂。它能够抑制过敏反应期间嗜酸性粒细胞趋化,可以标记抗过敏特性。 | |||
T22354 |
Levocetirizine Dihydrochloride
Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydrochloride is the R-enantiomer of Cetirizine, which gives it a higher affinity for the H1-receptor than the S-enantiomer. Due to this enhanced affinity, Levocetirizine Dihydrochloride is effective in treating allergic rhinitis and chronic idiopathic urticaria. | |||
T19233 |
Cetirizine D4 dihydrochloride
Cetirizine D4 dihydrochloride (1219803-84-5 free base) |
Others | Others |
Cetirizine D4 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist. | |||
T19234 |
Cetirizine D8 dihydrochloride
盐酸西替利嗪 D8 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Cetirizine D8 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist. | |||
T73981 | Deschloro Cetirizine dihydrochloride | ||
Deschloro Cetirizine Dihydrochloride 为 Cetirizine 杂质(impurity)。Cetirizine 属于第二代抗组胺药,作为羟嗪羧化代谢物,它表现为特异性、口服活性的长效组胺 H1 受体(histamine H1-receptor)拮抗剂。 | |||
T73962 | Cetirizine Impurity C dihydrochloride | ||
Cetirizine Impurity C dihydrochloride 为Cetirizine杂质之一,属于羟嗪的羧化代谢物,是第二代抗组胺剂中的一个。其为具有特异性且口服有效的H1受体(histamine H1-receptor)长效拮抗剂。 | |||
T2200 |
Hydroxyzine dihydrochloride
Hydroxyzine 2HCl,盐酸羟嗪 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) 是一种苯二氮卓抗组胺剂,是可口服的组胺 H1 受体和血清素拮抗剂,可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它还可以作为止吐剂和镇静剂,有缓解焦虑和紧张的作用。 |