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Search Results for " ccn2 "
Targets Recommended: EGFR

1

抑制剂 & 化合物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T80220 OK2

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
OK2CCN2/EGFR交互作用的特异性抑制剂,其通过结合CCN2的CT结构域,有效阻断了CCN2/EGFR的交互作用。该化合物适用于肾纤维化与慢性肾脏疾病研究。

化合物

OK2
Cat.No: T80220
Synonym:
Target: EGFR
Cat. No. Product Name Species Expression System
TMPK-01000 CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated

CTGF,CCN2,IBP-8,IGFBP8,Fisp12,CTG...

Human HEK293 Cells
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells wi...
TMPK-00672 CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)

CTGRP,CTGF,IBP-8,CCN2,NOV2,HCS

Rhesus HEK293 Cells
Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells. CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His ta...
TMPH-02568 CTGF/CCN2 Protein, Mouse, Recombinant (GST)

betaIG-M2,Connective tissue growth factor,Protein F...

Mouse E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
TMPH-01069 CTGF/CCN2 Protein, Human, Recombinant (His)

Hypertrophic chondrocyte-specific protein 24,CC...

Human E. coli
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. CTGF/CCN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.1 kDa and...
TMPJ-01161 CTGF/CCN2 Protein, Human, Recombinant

IGFBP-8,CCN family member 2,IBP-8,Connecti...

Human HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-25 KDa and the accession number is Q5M8T4.
TMPJ-01162 CTGF/CCN2 Protein, Human, Recombinant (hFc)

IGFBP8,Connective tissue growth factor,Hypertrophic chondroc...

Human HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 67-81 KDa and the accession number is Q5M8T4.
TMPJ-01163 CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)

CTGF,Connective tissue growth factor

Human HEK293 Cells
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physio...
TMPH-02594 MMP-13 Protein, Mouse, Recombinant (His)

Mouse E. coli
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone develop...

重组蛋白

CTGF/CCN2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01000
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00672
Species: Rhesus
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02568
Species: Mouse
Expression System: E. coli
CTGF/CCN2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01069
Species: Human
Expression System: E. coli
CTGF/CCN2 Protein, Human, Recombinant
Cat.No: TMPJ-01161
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-01162
Species: Human
Expression System: HEK293 Cells
CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
Cat.No: TMPJ-01163
Species: Human
Expression System: HEK293 Cells
MMP-13 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02594
Species: Mouse
Expression System: E. coli
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