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Cat. No.	Product Name	Target	Signaling Pathways
T10297L	AMG 487	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	AMG 487 是可口服的选择性趋化因子受体3拮抗剂，对 I-IP-10、I-ITAC 和 MIG 的 IC50 值分别为 8、15 和 36nM。
T70411	PS372424 HCl
	PS372424 is a specific agonist of human CXCR3. It has been shown to induce phosphorylation of ERK and block CXCL11 induced migration of CD45+ cells to air pouches generated on humanized mice.
T73148	ACT-777991
	ACT-777991为一种选择性、口服生效的CXCR3拮抗剂，于动物模型中展现出微粒体及肝细胞稳定性，能抑制活化T细胞向CXCL11迁移。
T62325	CXCR7 antagonist-1 hydrochloride
	CXCR7 antagonist-1 hydrochloride 是一种 CXCR7 拮抗剂，对 SDF-1 趋化因子（也称为 CXCL12 趋化因子）或 I-TAC（也称为 CXCL11）与趋化因子受体 CXCR7 结合具有抑制作用。CXCR7 antagonist-1 hydrochloride 能够用于肿瘤细胞增殖，肿瘤形成，炎症疾病和许多其他疾病的预防。
T36982	CXCR3 Antagonist 6c
	CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50= 0.06 μM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 μM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50= ~100 nM). 1.Cole, A.G., Stroke, I.L., Brescia, M.-R., et al.Identification and initial eva...