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Targets Recommended: CRFR

2

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TP2048L α-helical CRF 9-41 acetate

肾上腺皮质素释放因子多肽α-helical CRF 9-41乙酸盐,α-helical CRF 9-41 acetate(90880-23-2 Free base)

CRFR GPCR/G Protein
α-helical CRF 9-41 acetate 是 CRF2 的竞争性拮抗剂 (KB = 100 nM) 和 CRF1 的部分激动剂 (EC50 = 140 nM)。
T75891 α-Helical CRF(9-41) TFA

α-Helical CRF(9-41) TFA 是一种竞争性 CRF2受体拮抗剂,KB 约为 100 nM。α-Helical CRF(9-41) TFA 也是一种 CRF1受体的部分激动剂,EC50为 140 nM。

化合物

α-helical CRF 9-41 acetate
Cat.No: TP2048L
Synonym: 肾上腺皮质素释放因子多肽α-helical CRF 9-41乙酸盐,α-helical CRF 9-41 acetate(90880-23-2 Free base)
Target: CRFR
α-Helical CRF(9-41) TFA
Cat.No: T75891
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-00474 IL-22RA1 Protein, Cynomolgus, Recombinant (His)

CRF2-9,IL22R1,I...

Cynomolgus HEK293 Cells
IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activatio...
TMPK-01071 IL-22RA1 Protein, Mouse, Recombinant (hFc)

IL-22R α1,IL22R,zcytoR11...

Mouse HEK293 Cells
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPK-01105 IL-22RA1 Protein, Human, Recombinant (hFc)

IL-22R-alpha-1,CRF2-...

Human HEK293 Cells
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His)

VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...

Human HEK293 Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPY-03698 VEGF121b Protein, Human, Recombinant

MVCD1,VEGF,VPF,vascular endothelial growth factor A

Human HEK293 Cells
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.
TMPH-00005 YAP1 Protein, Human, Recombinant (Isoform 9, His)

YAP1-2delta

Human P. pastoris (Yeast)
YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.4 kDa; 80 kDa, reducing conditions and the accession number is P46937-9.
TMPK-00825 VEGF121 Protein, Human, Recombinant (His & Avi)

VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00826 VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

VAS,VEGFMGC70609,RP1-261G23.1,血管内...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPY-05268 Neurofascin Protein, Human, Recombinant (hFc), Biotinylated

NRCAML,neurofascin,NF

Human HEK293 Cells
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-9.

重组蛋白

IL-22RA1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00474
Species: Cynomolgus
Expression System: HEK293 Cells
IL-22RA1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01071
Species: Mouse
Expression System: HEK293 Cells
IL-22RA1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01105
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00865
Species: Human
Expression System: HEK293 Cells
VEGF121b Protein, Human, Recombinant
Cat.No: TMPY-03698
Species: Human
Expression System: HEK293 Cells
YAP1 Protein, Human, Recombinant (Isoform 9, His)
Cat.No: TMPH-00005
Species: Human
Expression System: P. pastoris (Yeast)
VEGF121 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00825
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00826
Species: Human
Expression System: HEK293 Cells
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05268
Species: Human
Expression System: HEK293 Cells
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