Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8344 |
CPTH2
|
Apoptosis; Histone Acetyltransferase | Apoptosis; Chromatin/Epigenetic |
CPTH2 是一种组蛋白乙酰基转移酶抑制剂。它选择性地抑制Gcn5对组蛋白 H3 的乙酰化,通过抑制乙酰转移酶p300 (KAT3B)诱导凋亡并降低透明细胞肾癌细胞系的侵袭性。 | |||
T22693 |
CPTH2 (hydrochloride) (357649-93-5 free base)
CPTH2 (hydrochloride) |
Others | Others |
CPTH2 is an inhibitor of the HAT activity of Gcn5. | |||
T35820 |
CAY10685
|
||
CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture associated with cancer and certain laminopathies. |