7
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10899 |
CU-CPT17e
|
TLR | Immunology/Inflammation |
CU-CPT17e 是多Toll 样受体激动剂,可激活TLR3、TLR8和TLR9。 | |||
T12408 |
Perhexiline maleate
|
Others; Mitochondrial Metabolism | Metabolism; Others |
Perhexiline maleate 是一种口服活性的 CPT1和 CPT2抑制剂,可降低脂肪酸的代谢。Perhexiline maleate 对大鼠心脏和肝脏CPT 1的IC50值分别为77 和 148 μM。 | |||
T13113 |
Teglicar
|
Others | Others |
Teglicar is a selective and reversible liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor. | |||
T83767 |
4-Hydroxyphenylglyoxylic Acid
UK 22486 |
||
4-Hydroxyphenylglyoxylic acid 是一种抑制剂,针对 carnitine palmitoyltransferase 1 (CPT1),同时也是前药 oxfenicine 的活性代谢物。在 200 至 1,000 µM 的浓度范围内,该化合物能够抑制离体大鼠肝线粒体中的 CPT1,并能够抑制离体大鼠肝细胞中的油酸氧化。 | |||
T68618 |
S-(-)-Etomoxir
|
||
S-(-)-Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1) -- a molecule required for the oxidation of long-chain acyl CoA esters. | |||
T60510 |
Perhexiline
|
||
Perhexiline 是一种口服活性的 CPT1和 CPT2抑制剂,可降低脂肪酸的代谢。Perhexiline 可以穿过血脑屏障 (BBB)具有抗癌活性。Perhexiline 诱导肝细胞中的线粒体功能障碍和细胞凋亡。因此,Perhexiline 可用于研究癌症和心绞痛等心血管疾病。 | |||
T73829 |
Malonyl CoA
|
||
Malonyl CoA是脂肪酸生物合成的重要底物,同时也担任脂肪酸氧化过程中的抑制剂角色。此外,Malonyl CoA亦作为线粒体肉碱棕榈酰转移酶1(CPT1)的可逆性抑制剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01050 |
CPT2 Protein, Human, Recombinant (His & Myc)
Carnitine O-palmitoyltransferase 2, mitochondrial,CPT |
Human | E. coli |
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters. CPT2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with ... | |||
TMPH-03328 |
Mcpt1 Protein, Rat, Recombinant (Myc)
|
Rat | E. coli |
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650. |