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Search Results for " cpr "

Targets Recommended: PDE

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T39341	FCPR03	PDE	Metabolism
	FCPR03 是一种特异性磷酸二酯酶 4 (PDE4) 抑制剂，对 PDE4B1、PDE4D7 和 PDE4 催化结构域的 IC50 分别为 31 nM、47 nM 和 60 nM。 FCPR03 具有神经保护、抗炎和抗抑郁样作用。
T75168	Homo-BacPROTAC7
	Homo-BacPROTAC7 是一个 ClpC1NTDBacPROTAC 降解剂，可以靶向 ClpC2。Homo-BacPROTAC7 能有效杀死 M. tuberculosis。
T75171	BacPROTAC-1
	BacPROTAC-1 是一个 mSABacPROTAC 降解剂。BacPROTAC-1 对 mSA 和 ClpCNTD 具有高亲和力 (KD 分别为 3.9 μM 和 2.8 μM)。
T39269	cPrPMEDAP
	cPrPMEDAP, an intermediate metabolite of GS-9219, acts as a prodrug for the guanine nucleotide analog PMEG, demonstrating antiproliferative activity. It is negatively charged at physiological pH, resulting in poor skin permeability.
T75167	Homo-BacPROTAC6
	Homo-BacPROTAC6 是一个 ClpC1NTDBacPROTAC 降解剂，可以靶向 ClpC2。Homo-BacPROTAC7 能有效杀死M. tuberculosis。
T7826	6-Chloropurine riboside	Others	Others
	6-Chloropurine riboside （6-CPR）是一种嘌呤核苷类似物，已被发现具有广泛的生物活性。它可以抑制肿瘤细胞的生长并诱导其凋亡，还被证明具有抗炎、抗病毒和抗真菌的特性，也被发现具有神经保护作用，并已用于治疗神经疾病。

化合物

6-Chloropurine riboside

Cat.No: T7826

Synonym:

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02505	Carboxypeptidase B2 Protein, Mouse, Recombinant (His) AI255929,4930405E17Rik,Cpu,TAFI,1110032P04Rik,CPR,c...	Mouse	HEK293 Cells
	Carboxypeptidase B2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q9JHH6.
TMPH-02801	CYPOR Protein, Mouse, Recombinant (His) CYPOR,P450R,CPR,NADPH--cytochrome P450 reductase,PO...	Mouse	E. coli
	CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-01748	CYPOR Protein, Human, Recombinant (GST) NADPH--cytochrome P450 reductase,P450R,CPR,POR,CYPO...	Human	E. coli
	This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. CYPOR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 102.9 kDa and the accession number is P16435.
TMPH-02141	CYP21A2 Protein, Human, Recombinant (His) Cytochrome P450 21,CYP21A2,Cytochrome P450-C21B,Cytochrome P...	Human	P. pastoris (Yeast)
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02140	CYP21A2 Protein, Human, Recombinant (E. coli, His) Cytochrome P-450c21,Cytochrome P450-C21B,CYP21,21-OHase,Cyto...	Human	E. coli
	A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02139	CYP17A1 Protein, Human, Recombinant (GST) Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17,S17AH,Cytochrome ...	Human	E. coli
	A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow...