Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1565 |
Deferiprone
去铁酮,Deferidone,CP20 |
Others; HCV Protease; Ferroptosis; UGT | Apoptosis; Metabolism; Microbiology/Virology; Others; Proteases/Proteasome |
Deferiprone (Deferidone) 是口服活性铁螯合剂,可研究地中海贫血中的输血性铁过载。 | |||
T71401 | Oxaliplatin-d10 | ||
Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.... |