Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35338 |
CP2
|
Histone Demethylase | Chromatin/Epigenetic |
CP2是一种环肽,能够抑制JmjC histone demethylases KDM4,对KDM4A 和KDM4C 的IC50分别为42 nM 和29 nM。 | |||
T3684 |
CP21R7
CP21 |
GSK-3; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
CP21R7 (CP21) 是一种 GSK-3β抑制剂,其 IC50=1.8 nM。它也是一种 PKCα抑制剂,其 IC50=1900 nM。 | |||
T71870 |
CP21
|
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CP21 is an iron chelator that binds to iron in a 3:1 (ligand:iron) ratio. It is active against P. falciparum when used at concentrations of 10 and 100 µM. CP21 inhibits production of prostaglandin I2 induced by epinephrine, arachidonic acid, or A23187 in isolated rat aortic rings with IC50 values of 1.3, 1.3, and 1.4 mM, respectively. It inhibits glutamate-induced oxytosis, as well as decreases iodoacetic acid-induced cytotoxicity in an in vitro model of ischemia, in HT22 mouse hippocampal cells... | |||
T69186 | CP26 | ||
CP26 is a novel inhibitor of ER-to-cytosol protein dislocation, exhibiting anti-dengue and anti-Zika virus activity. | |||
T24598 |
BrBzGCp2
p BrBzGSH(Cp)2,BBGC,pBrBzGSH(Cp)2,p-BrBzGSH(Cp)2,BBGD |
||
p-BrBzGSH(Cp)2 is a glyoxylase 1 inhibitor. In orthotopic mouse models, it acts by increasing DNA-AGEs, stimulating RAGE expression, and inhibiting brain tumor growth. | |||
T81693 |
NCP2 Anchor
|
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NCP2 Anchor用于合成外显子跳跃寡聚物偶联物。它的偶联物与人抗肌萎缩蛋白基因特定靶位点配对互补,从而诱导外显子52的跳跃。该偶联物常应用于肌肉萎缩症的科学研究。 |